Table 2.
Pooled meta‐analyses results of the current study
| Polymorphisms | Population | Sample size | Dominant comparison | Recessive comparison | Overdominant comparison | Allele comparison | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| p value | OR (95%CI) | p value | OR (95%CI) | p value | OR (95%CI) | p value | OR (95%CI) | |||
| rs1799983 G/T | Overall | 1792/1936 | .21 | 0.84 (0.64–1.10) | .33 | 1.26 (0.80–1.98) | .24 | 1.09 (0.94–1.27) | .14 | 0.83 (0.64–1.06) |
| Caucasian | 577/838 | .71 | 0.96 (0.78–1.19) | .26 | 0.81 (0.56–1.17) | .30 | 1.12 (0.90–1.39) | .82 | 1.02 (0.87–1.20) | |
| East Asian | 993/774 | .20 | 0.71 (0.42–1.20) | .20 | 1.66 (0.76–3.61) | .55 | 1.13 (0.76–1.68) | .15 | 0.69 (0.42–1.14) | |
| aSAH | 944/1255 | .10 | 0.77 (0.56–1.05) | .10 | 1.57 (0.92–2.70) | .24 | 1.11 (0.93–1.34) | .06 | 0.75 (0.55–1.01) | |
| IA | 848/681 | .85 | 0.95 (0.55–1.64) | .32 | 0.77 (0.46–1.29) | .75 | 1.09 (0.65–1.83) | .89 | 0.97 (0.60–1.56) | |
| rs2070744 T/C | Overall | 2159/2291 | .05 | 0.87 (0.76–1.00) | .47 | 1.10 (0.85–1.42) | .10 | 1.12 (0.98–1.29) | .06 | 0.90 (0.80–1.00) |
| Caucasian | 518/772 | .69 | 1.05 (0.83–1.32) | .71 | 0.94 (0.68–1.30) | .89 | 0.98 (0.79–1.23) | .64 | 1.04 (0.88–1.22) | |
| East Asian | 1419/1195 | .01 | 0.77 (0.63–0.94) | .16 | 1.42 (0.87–2.32) | .04 | 1.24 (1.01–1.52) | .006 | 0.78 (0.66–0.93) | |
| aSAH | 977/132 | .21 | 0.82 (0.59–1.12) | .86 | 1.03 (0.75–1.40) | .28 | 1.11 (0.92–1.33) | .27 | 0.85 (0.64–1.31) | |
| IA | 1182/968 | .09 | 0.83 (0.67–1.03) | .30 | 1.27 (0.81–2.01) | .21 | 1.15 (0.93–1.42) | .06 | 0.84 (0.70–1.01) | |
| rs869109213 VNTR | Overall | 1443/1741 | .49 | 0.90 (0.66–1.22) | .26 | 1.32 (0.81–2.14) | .65 | 1.08 (0.78–1.48) | .40 | 0.90 (0.70–1.15) |
| Caucasian | 525/777 | .62 | 0.82 (0.37–1.82) | .48 | 0.77 (0.37–1.61) | .53 | 1.34 (0.54–3.32) | .79 | 0.93 (0.53–1.63) | |
| East Asian | 696/640 | .72 | 0.95 (0.71–1.27) | .12 | 2.19 (0.82–5.86) | .83 | 0.97 (0.72–1.31) | .39 | 0.89 (0.68–1.16) | |
| aSAH | 685/1019 | .24 | 0.72 (0.41–1.25) | .21 | 1.48 (0.80–2.75) | .33 | 1.33 (0.74–2.40) | .19 | 0.75 (0.49–1.15) | |
| IA | 758/722 | .53 | 1.09 (0.84–1.42) | .81 | 1.10 (0.50–2.41) | .49 | 0.91 (0.69–1.19) | .60 | 1.07 (0.84–1.35) | |
Abbreviations: aSAH, aneurysmal subarachnoid hemorrhage; CI, confidence interval; IA, intracranial aneurysm; OR, odds ratio.
The values in bold represent there is statistically significant differences between cases and controls.