Table 1.
Effect of DCW on arsenic induced alteration in total protein, MDA, GSH, SOD, CAT and NO levels.
| Parameter (n = 6) | Normal | Arsenic control | Arsenic + Apocynin (10 mg/kg) | Arsenic + DCW (200 mg/kg) | Arsenic + DCW (400 mg/kg) |
|---|---|---|---|---|---|
| Total protein (mg/ml) | 0.78 ± 0.01 | 0.56 ± 0.05∗ | 0.77 ± 0.02# | 0.71 ± 0.05# | 0.72 ± 0.01# |
| MDA (nM/mg of protein) | 10.83 ± 0.26 | 19.85 ± 1.60∗ | 11.02 ± 0.43# | 15.68 ± 0.73# | 12.29 ± 0.81# |
| GSH (μM/mg of protein) | 26.75 ± 1.12 | 9.54 ± 0.69∗ | 25.71 ± 0.62# | 19.89 ± 0.79# | 23.80 ± 0.83# |
| SOD (U/mg of protein) | 20.04 ± 0.75 | 2.11 ± 0.19∗ | 12.19 ± 0.75# | 8.68 ± 0.62# | 9.80 ± 0.26# |
| Catalase (μM of H2O2 consumed/min/mg) | 768.04 ± 9.41 | 167.7 ± 6.6∗ | 764.6 ± 5.77# | 372.71 ± 5.12# | 570.93 ± 1.95# |
| NO (μM/mg of protein) | 14.50 ± 0.24 | 32.4 ± 0.32∗ | 17.26 ± 0.41# | 24.18 ± 0.32# | 19.29 ± 0.29# |
Data were expressed as mean ± SD (n = 6); analysed by one way ANOVA followed by Bonferroni's post test.∗ = p < 0.05, considered statistically significant when compared to the normal and # = p < 0.05 when compared to the disease control.