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. 2020 May 12;20:411. doi: 10.1186/s12885-020-06893-3

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Anti-tumor effects of radiation therapy (RT) or anti-CD73 antibody used alone. Tumor bearing mice received local RT to subcutaneous (sc) tumors (3 fractions of 4 Gy) as described above on days 12, 14, 16 and intraperitoneal injection of 200 μg anti-CD73 mAb or Rat IgG2a isotype control at days 12, 14, 16, 19, 22 and 25. All of the mice were sacrificed on day 28, and the weight of sc tumors and number of macroscopic metastatic nodules in the lungs evaluated. P value was calculated with one-way ANOVA followed by Tukey test and * showed p < 0.05