Fig. 3.

Anti-tumor effects of anti-CD73 antibody combined with radiation therapy (RT). Tumor bearing mice received local RT together with immunotherapy using the same protocol shown in Fig. 2. The growth of subcutaneous (sc) tumors was evaluated by their volume calculated by length×width²/2 (b). All mice were sacrificed on day 28, and the volume of sc tumor (a) as well as the number of macroscopic metastatic nodules (c, d) in the lungs counted. P value was calculated with the Mann-Whitney test and * showed p < 0.05