Table 3.
Clinical characteristics and antibiotic prescribing among patients with severe infections at two private sector hospitals
| NTH, n (%) |
TH, n (%) |
Odds ratio (95% CI) |
P-value | |
|---|---|---|---|---|
|
All included patients, n (%) |
2504 (100) | 1262 (100) | ||
| Mean age | 49.2 | 47.1 | < 0.01 | |
| Women, n (%) | 894 (36) | 301 (24) | ||
| Men, n (%) | 1610 (64) | 961 (76) | ||
| Patients prescribed ABs, n (%) | 2294 (92) | 1122 (89) | 1.36 (1.08, 1.72) | < 0.05 |
| AB prescriptions, n (n of prescriptions per patients prescribed AB) | 18,751 (8) | 24,956 (22) | ||
| Cellulitis | 388 (15) | 402 (32) | ||
| Mean age | 50.4 | 48.7 | 0.16 | |
| Women, n (%) | 101 (26) | 79 (20) | ||
| Men, n (%) | 287 (74) | 323 (80) | ||
| Patients prescribed ABs, n (%) | 354 (91) | 362 (90) | 1.15 (0.69,1.91) | 0.57 |
| AB prescriptions, n (n of prescriptions per patients prescribed AB) | 3505 (10) | 8608 (24) | ||
| Endocarditis | 7 (0) | 2 (0) | ||
| Mean age | 45.6 | 35.0 | 0.21 | |
| Women, n (%) | 3 (43) | 2 (100) | ||
| Men, n (%) | 4 (57) | 0 (0) | ||
| Patients prescribed ABs, n (%) | 6 (86) | 1 (50) | 6 (0.04,547.49) | 0.28 |
| AB prescriptions, n (n of prescriptions per patients prescribed AB) | 33 (6) | 54 (54) | ||
| Epiglottitis | 12 (0) | 1 (0) | ||
| Mean age | 35.8 | 40.0 | 0.25 | |
| Women, n (%) | 6 (50) | 0 (0) | ||
| Men, n (%) | 6 (50) | 1 (100) | ||
| Patients prescribed ABs, n (%) | 11 (92) | 1 (100) | – | – |
| AB prescriptions, n (n of prescriptions per patients prescribed AB) | 57 (5) | 2 (2) | ||
| Meningitis | 186 (7) | 38 (3) | ||
| Mean age | 40.6 | 37.0 | 0.24 | |
| Women, n (%) | 90 (48) | 15 (39) | ||
| Men, n (%) | 96 (52) | 23 (61) | ||
| Patients prescribed ABs, n (%) | 167 (90) | 27 (71) | 3.58 (1.37, 8.93) | < 0.05 |
| AB prescriptions, n (n of prescriptions per patients prescribed AB) | 1126 (7) | 442 (16) | ||
| Peritonitis | 431 (17) | 252 (20) | ||
| Mean age | 44.4 | 44.0 | 0.71 | |
| Women, n (%) | 52 (12) | 35 (14) | ||
| Men, n (%) | 379 (88) | 217 (86) | ||
| Patients prescribed ABs, n (%) | 402 (93) | 233 (92) | 1.13 (0.58, 2.14) | 0.69 |
| AB prescriptions, n (n of prescriptions per patients prescribed AB) | 4909 (12) | 6715 (29) | ||
| Pneumonia | 761 (30) | 410 (32) | ||
| Mean age | 49.6 | 48.4 | 0.30 | |
| Women, n (%) | 294 (39) | 100 (24) | ||
| Men, n (%) | 467 (61) | 310 (76) | ||
| Patients prescribed ABs, n (%) | 692 (91) | 366 (89) | 1.21 (0.78, 1.83) | 0.36 |
| AB prescriptions, n (n of prescriptions per patients prescribed AB) | 4686 (7) | 6179 (17) | ||
| Pyelonephritis | 71 (3) | 3 (0) | ||
| Mean age | 42.3 | 26.7 | < 0.01 | |
| Women, n (%) | 32 (45) | 2 (67) | ||
| Men, n (%) | 39 (55) | 1 (33) | ||
| Patients prescribed ABs, n (%) | 68 (96) | 2 (67) | 11.33 (0.14,262.11) | 0.16 |
| AB prescriptions, n (n of prescriptions per patients prescribed AB) | 518 (8) | 89 (45) | ||
| Septic arthritis | 3 (0) | 38 (3) | ||
| Mean age | 43.3 | 45.0 | 0.93 | |
| Women, n (%) | 1 (33) | 15 (39) | ||
| Men, n (%) | 2 (67) | 23 (61) | ||
| Patients prescribed ABs, n (%) | 3 (100) | 29 (76) | – | – |
| AB prescriptions, n (n of prescriptions per patients prescribed AB) | 15 (5) | 1159 (40) | ||
| Sepsis | 645 (26) | 116 (9) | ||
| Mean age | 54.9 | 49.2 | < 0.01 | |
| Women, n (%) | 315 (49) | 53 (46) | ||
| Men, n (%) | 330 (51) | 63 (54) | ||
| Patients prescribed ABs, n (%) | 591 (92) | 101 (87) | 1.6 (0.82,3.0) | 0.11 |
| AB prescriptions, n (n of prescriptions per patients prescribed AB) | 3902 (7) | 1708 (17) |
Notes: P-values for mean age were obtained by linear regression. Odds ratios, p-values and CIs for antibiotic prescribing were obtained by chi-square tests. Statistically significant p-values are marked in bold font
Abbreviations: AB Antibiotic, CI Confidence interval, n Number, NTH Non-teaching hospital, OR Odds ratio, TH Teaching hospital