Table 2.

Cox proportional hazard model of clinical parameters and TMEM240 mRNA expression level associated with Taiwan CRC patients

	Multivariate analysis
Variable	HR	95% CI		p value
		Lower	Upper
Overall survival
Age	0.291	0.051	1.667	0.166
Sex	0.308	0.054	1.740	0.182
Stage	4.702	1.695	13.041	0.003
Location	2.970	0.985	8.951	0.053
Differentiation	0.599	0.030	11.897	0.737
DNA methylation	1.005	1.001	1.010	0.028
mRNA expression	0.196	0.055	0.704	0.012
Cancer specific survival
Age	0.198	0.025	1.584	0.127
Sex	0.245	0.035	1.718	0.157
Stage	7.658	2.083	28.161	0.002
Location	4.055	1.257	13.083	0.019
Differentiation	0.463	0.017	12.307	0.646
DNA methylation	1.006	1.001	1.011	0.025
mRNA expression	0.142	0.035	0.587	0.007
Recurrence-free survival
Age	0.360	0.088	1.473	0.155
Sex	0.358	0.095	1.345	0.128
Stage	9.385	3.249	27.112	< 0.000
Location	2.338	0.941	5.809	0.067
Differentiation	0.873	0.143	5.338	0.883
DNA methylation	1.004	1.000	1.008	0.045
mRNA expression	0.289	0.100	0.837	0.022