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. 2020 Apr 24;15(1):36. doi: 10.5334/gh.793

Table 2.

Statistical Models Evaluating the Association between Heart Failure and Insulin Resistance Considering the Potential Confounders.

Insulin resistance Model 1 Model 2 Model 3

OR 95% CI p-value OR 95% CI p-value OR 95% CI p-value

CCM (Yes/No) 0.68 0.11–4.31 0.683 4.08 1.55–10.74 0.004 0.38 0.02–6.81 0.516
Sex (Men vs Women) 0.49 0.24–1.01 0.054 0.56 0.26–1.21 0.142 0.11 0.01–1.57 0.103
Age, years (>60 vs ≤60) 0.18 0.07–0.45 0.000 0.19 0.08–0.49 0.001 1 omitted
MAP, mmHg (>100 vs ≤100) 2.93 1.21–7.11 0.017 2.83 1.12–7.11 0.027 4.34 0.04–465.2 0.538
Alcohol consumption (Yes/No) 0.55 0.24–1.22 0.142 0.54 0.23–1.26 0.155 0.19 0.01–4.44 0.306
HWI (Yes/No) 2.02 0.47–8.66 0.345
Group*HWI interaction 5.94 0.78–44.96 0.084
Total Cholesterol, mg/dl (>200 vs ≤200) 1.61 0.81–3.23 0.175 1.70 0.80–3.61 0.165 0.77 0.04–14.2 0.861
CRP mg/dl (>3 vs ≤3) 1.85 0.87–3.94 0.109 1.59 0.71–3.61 0.260 9.79 0.52–183.7 0.127
Physical activity (Low)
      Moderate 1.38 0.59–3.19 0.452 1.18 0.48–2.87 0.718 8.99 0.48–167.4 0.141
      High 1.06 0.41–2.72 0.909 0.98 0.35–2.73 0.976 0.30 0.01–19.53 0.576

Abbreviations: CCM: Chronic Chagas Cardiomyopathy; MAP: Mean arterial pressure; HWI: Hip Waist Index; CRP: Reactive protein C.

Model 1 = Analysis with HWI interaction.

Model 2 = Including only patients with HWI alteration.

Model 3 = Including only patients without HWI alteration.