Figure 1.

Antidiabetic effects of MFE on alloxan-induced diabetic mice. Mice were administered with MFE (0, 100, and 200 mg/kg orally) or glibenclamide (5 mg/kg orally) once a day for 12 weeks after an alloxan challenge (50 mg/kg). Body weight, blood glucose levels, and water and food intake were monitored once per week during the experimental period. In the oral glucose tolerance test, fasted mice were administered with a glucose solution (1 g/kg orally) before they were sacrificed. Data are expressed as the mean ± SEM. ^∗p < 0.05 and ^∗∗p < 0.01 versus the alloxan-treated group. (a) Body weight. (b) Food intake. (c) Water intake. (d) Blood glucose. (e) Oral glucose tolerance.