Table 5.

Electrolyte levels at baseline, in placebo, and spironolactone-treated patients.

	AST (U/L)	ALT (U/L)	BUN (mg/dl)	Creatinine (mg/dl)	GFR (ml/min/1.73 m2)	Na (mEq/L)	K (mEq/L)
Placebo	27 ± 12	23 ± 14	14 ± 3	0.83 ± 0.17	85 ± 20	142 ± 3	4.33 ± 0.36
Spironolactone	25 ± 14	21 ± 14	13 ± 4	0.85 ± 0.18	82 ± 20	141 ± 3	4.38 ± 0.37
P value	NS	NS	NS	NS	NS	0.041	NS

AST: aspartate aminotransferase; ALT: alanine aminotransferase; GFR: glomerular filtration rate; K: potassium; Na: sodium.