2. Cytology with p16/Ki-67 dual staining and TCT results in HPV 16/18-positive women with different histology results.
DS/TCT | n | |||||
Chronic cervicitis | CIN I | CIN II | CIN III | Cancer | Total | |
TCT, Thinprep cytologic test; HPV, human papillomavirus; DS, p16/Ki-67 dual-stained cytology; ASCUS, atypical squamous cells of undetermined significance; NILM, negative for intraepithelial lesions or malignancy. | ||||||
HPV 16+ | ||||||
+/≥ASCUS | 2/3 | 21/28 | 42/34 | 13/9 | 10/9 | 88 |
−/NILM | 10/9 | 67/60 | 6/14 | 0/4 | 0/1 | 83 |
Total | 12 | 88 | 48 | 13 | 10 | 171 |
HPV 18+ | ||||||
+/≥ASCUS | 0/1 | 9/10 | 10/9 | 0 | 3/1 | 22 |
−/NILM | 5/4 | 22/21 | 6/7 | 0 | 0/2 | 33 |
Total | 5 | 31 | 16 | 0 | 3 | 55 |