1. Criteria of skip of chemotherapy.
| Variables | Criteria |
| ANC, absolute neutrophil count. | |
| ANC | More than 750/mm3 |
| Platelet | More than 75,000/mm3 |
| Infection and fever | No fever (over 38.3°C
without infection) |
| Diarrhea | Less than grade 1 |
| Other non-hematological adverse events | Less than grade 2 |