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. 2020 Apr;32(2):218–227. doi: 10.21147/j.issn.1000-9604.2020.02.09

5. Response of treatment.

Cases Histology Response Distant metastasis PFS (month) OS (month) Outcome
DL, dose level; ADC, adenocarcinoma; SCC, squamous cell carcinoma; ADSQ, adeno-squamous cell carcinoma; SD, stable disease; CR, complete response; PR, partial response; NE, not evaluable due to discontinuation of protocol treatment; N, none; PAN, para aortic lymph node; N/A, not applicable; DOD, died of disease; AWD, alive with disease; NED, no evidence of disease.
DL1-1 ADC SD N 5.6 21.6 DOD
DL1-2 SCC CR N 7.0 16.3 DOD
DL1-3 SCC CR Virchow 3.1 19.4 AWD
DL2-1 ADC CR N N/A 15.2 DOD
DL2-2 SCC CR PAN 3.5 56.4 AWD
DL2-3 SCC CR Liver, PAN 5.4 7.4 DOD
DL2-4 ADC PR N N/A 23.8 NED
DL2-5 SCC CR N N/A 28.0 NED
DL3-1 ADSQ PR Lung N/A 45.3 NED
DL3-2 SCC SD Virchow 6.4 30.5 AWD
DL3-3 ADC CR N N/A 38.2 NED
DL3-4 EMC SD N N/A 7.8 AWD
DL3-5 SCC CR N 7.0 28.2 NED
DL3-6 SCC CR N N/A 6.5 NED
DL4-1 SCC PR N N/A 29.8 NED
DL4-2 ADC NE N 4.1 6.4 DOD
DL4-3 SCC NE PAN 3.5 10.1 AWD