2. DFS, first-line PFS and OS according to treatment group. (A) DFS according to treatment group (P=0.002); (B) First-line PFS according to treatment group (P=0.907); (C) First-line PFS in patients with liver metastases according to treatment group (P=0.078); (D) OS from start of treatment of patients according to treatment group (P=0.090). DFS, disease-free survival; PFS, progression-free survival; OS, overall survival.