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. 2020 Apr;32(2):149–162. doi: 10.21147/j.issn.1000-9604.2020.02.03

1. Baseline characteristics of patients according to type of first-line therapy.

Characteristics NPCT (n=129) [n (%)] PBCT (n=91) [n (%)] P
DFS, disease-free survival; 95% CI, 95% confidence interval; NPCT, non-platinum-based chemotherapy; PBCT, platinum-based chemotherapy; *, Including digestive tract, pancreatic and prostate cancer and blood system tumors; **, Including lung, liver and brain metastases.
Age (year)
 Median (range) 51 (25−75) 46 (21−66) 0.001
 ≤50 64 (49.6) 62 (68.1) 0.006
 >50 65 (50.4) 29 (31.9)
Family history
 Breast/ovarian cancer 12 (9.3) 9 (9.9) 0.416
 Other cancers* 16 (12.4) 17 (18.7)
 No 101 (78.3) 65 (71.4)
Histology of primary tumor
 Invasive ductal carcinoma 113 (87.6) 79 (86.8) 0.063
 Invasive lobular carcinoma 8 (6.2) 1 (1.1)
 Others 8 (6.2) 11 (12.1)
Diagnosed triple negative
 Primary tumor 111 (86.0) 79 (86.8) 0.870
 Metastatic sites 18 (14.0) 12 (13.2)
Tumor grade
 I 1 (0.8) 0 (0) 0.624
 II 49 (38.0) 30 (33.0)
 III 44 (34.1) 33 (36.3)
 Unknown 35 (27.1) 28 (30.8)
Ki67 index
 ≤14% 12 (9.3) 9 (9.9) 0.459
 15%−50% 50 (38.8) 26 (28.6)
 >50% 45 (34.9) 39 (42.9)
 Unknown 22 (17.1) 17 (18.7)
DFS (month)
 Median (95% CI) 24.3 (20.6−28.0) 14.3 (11.9−16.7) 0.002
 ≤24 66 (51.2) 69 (75.8) 0.000
 >24 63 (48.8) 22 (24.2)
Metastatic site
 Node 56 (43.4) 43 (47.3) 0.573
 Bone 31 (24.0) 20 (22.0) 0.722
 Chest wall 23 (17.8) 18 (19.8) 0.714
 Lung 41 (31.8) 30 (33.0) 0.853
 Liver 24 (18.6) 13 (14.3) 0.399
 Brain 6 (4.7) 2 (2.2) 0.554
 Other sites 13 (10.1) 20 (22.0) 0.015
Number of metastases
 1 88 (68.2) 52 (57.1) 0.153
 2 22 (17.1) 25 (27.5)
 ≥3 19 (14.7) 14 (15.4)
Visceral metastasis**
 No 72 (55.8) 51 (56.0) 0.973
 Yes 57 (44.2) 40 (44.0)