1. Baseline characteristics of patients according to type of first-line therapy.
| Characteristics | NPCT (n=129) [n (%)] | PBCT (n=91) [n (%)] | P |
| DFS, disease-free survival; 95% CI, 95% confidence interval; NPCT, non-platinum-based chemotherapy; PBCT, platinum-based chemotherapy; *, Including digestive tract, pancreatic and prostate cancer and blood system tumors; **, Including lung, liver and brain metastases. | |||
| Age (year) | |||
| Median (range) | 51 (25−75) | 46 (21−66) | 0.001 |
| ≤50 | 64 (49.6) | 62 (68.1) | 0.006 |
| >50 | 65 (50.4) | 29 (31.9) | |
| Family history | |||
| Breast/ovarian cancer | 12 (9.3) | 9 (9.9) | 0.416 |
| Other cancers* | 16 (12.4) | 17 (18.7) | |
| No | 101 (78.3) | 65 (71.4) | |
| Histology of primary tumor | |||
| Invasive ductal carcinoma | 113 (87.6) | 79 (86.8) | 0.063 |
| Invasive lobular carcinoma | 8 (6.2) | 1 (1.1) | |
| Others | 8 (6.2) | 11 (12.1) | |
| Diagnosed triple negative | |||
| Primary tumor | 111 (86.0) | 79 (86.8) | 0.870 |
| Metastatic sites | 18 (14.0) | 12 (13.2) | |
| Tumor grade | |||
| I | 1 (0.8) | 0 (0) | 0.624 |
| II | 49 (38.0) | 30 (33.0) | |
| III | 44 (34.1) | 33 (36.3) | |
| Unknown | 35 (27.1) | 28 (30.8) | |
| Ki67 index | |||
| ≤14% | 12 (9.3) | 9 (9.9) | 0.459 |
| 15%−50% | 50 (38.8) | 26 (28.6) | |
| >50% | 45 (34.9) | 39 (42.9) | |
| Unknown | 22 (17.1) | 17 (18.7) | |
| DFS (month) | |||
| Median (95% CI) | 24.3 (20.6−28.0) | 14.3 (11.9−16.7) | 0.002 |
| ≤24 | 66 (51.2) | 69 (75.8) | 0.000 |
| >24 | 63 (48.8) | 22 (24.2) | |
| Metastatic site | |||
| Node | 56 (43.4) | 43 (47.3) | 0.573 |
| Bone | 31 (24.0) | 20 (22.0) | 0.722 |
| Chest wall | 23 (17.8) | 18 (19.8) | 0.714 |
| Lung | 41 (31.8) | 30 (33.0) | 0.853 |
| Liver | 24 (18.6) | 13 (14.3) | 0.399 |
| Brain | 6 (4.7) | 2 (2.2) | 0.554 |
| Other sites | 13 (10.1) | 20 (22.0) | 0.015 |
| Number of metastases | |||
| 1 | 88 (68.2) | 52 (57.1) | 0.153 |
| 2 | 22 (17.1) | 25 (27.5) | |
| ≥3 | 19 (14.7) | 14 (15.4) | |
| Visceral metastasis** | |||
| No | 72 (55.8) | 51 (56.0) | 0.973 |
| Yes | 57 (44.2) | 40 (44.0) | |