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. 2020 Apr;32(2):149–162. doi: 10.21147/j.issn.1000-9604.2020.02.03

7. CBR, PFS and OS with or without deleterious gBRCA mutations according to type of chemotherapy .

Results PBCT (n=44) NPCT (n=70)
With (n=7) Without (n=37) P With (n=7) Without (n=63) P
CBR, clinical benefit rate; PFS, progression-free survival; OS, overall survival; gBRCA, germline BRCA1/2; PBCT, platinum-based chemotherapy; NPCT, non-platinum-based chemotherapy; 95% CI, 95% confidence interval.
CBR 85.7% (6/7) 35.1% (13/37) 0.039 57.1% (4/7) 39.7% (25/63) 0.627
PFS [median (95% CI)] (month) 14.9 (6.9−22.9) 5.3 (4.0−6.6) 0.001 5.8 (1.2−10.4) 5.1 (3.8−6.4) 0.677
OS [median (95% CI)] (month) 26.5 (−) 15.5 (10.9−20.2) 0.161 14.5 (10.4−18.6) 0.075