9. Summary of deleterious gBRCA mutations .

No. of patients	Gene	Location	Mutation type	AA change
gBRCA, germline BRCA1/2.
193	BRCA1	c.3329dupA	Frameshift	Q1111Afs*5
126	BRCA1	c.3627dupA	Frameshift	E1210Rfs*9
105	BRCA1	c.3756_3759delGTCT	Frameshift	S1253Rfs*10
198	BRCA1	c.4065_4068delTCAA	Frameshift	N1355Kfs*10
210	BRCA1	c.5470_5477delTGCCCAAT	Frameshift	I1824Dfs*
107	BRCA1	c.981_982delAT	Nonsense	C328*
157	BRCA1	c.376C>T	Nonsense	Q126*
216	BRCA1	c.3841C>T	Nonsense	Q128*
98	BRCA1	c.4612C>T	Nonsense	Q1538*
10	BRCA2	c.2059_2063delGATTA	Frameshift	D687*
215	BRCA2	c.3319C>T	Nonsense	Q1107*
83	BRCA2	c.4240delA	Frameshift	T1414Rfs*5
136	BRCA2	c.6288_6289delTA	Frameshift	T2097Vfs*
113	BRCA2	c.6628G>T	Nonsense	E2210*