1. Clinicopathological factors associated with peritoneal dissemination in patients with gastric cancer.
Variables | n (%) | P | ||
Total (N=1,586) | Development set (n=1,112) | Validation set (n=474) | ||
SRCC, signet-ring cell carcinoma. | ||||
Sex | 0.395 | |||
Male | 1,060 (66.8) | 751 (67.5) | 309 (65.2) | |
Female | 526 (33.2) | 361 (32.5) | 165 (34.8) | |
Age (year) | 0.005 | |||
<55 | 600 (37.8) | 446 (40.1) | 154 (32.5) | |
≥55 | 986 (62.2) | 666 (59.9) | 320 (67.5) | |
Tumor location | 0.009 | |||
Proximal | 577 (36.4) | 423 (38.1) | 154 (32.5) | |
Middle | 317 (20.0) | 229 (20.6) | 88 (18.6) | |
Distal | 636 (40.1) | 415 (37.3) | 221 (46.6) | |
Entire | 20 (1.3) | 16 (1.4) | 4 (0.8) | |
Residual | 36 (2.2) | 29 (2.6) | 7 (1.5) | |
Tumor size (cm) | <0.001 | |||
≤5 | 1,067 (67.3) | 655 (58.9) | 412 (86.9) | |
>5 | 519 (32.7) | 457 (41.1) | 62 (13.1) | |
Pathological type | <0.001 | |||
Non-SRCC | 1,287 (81.1) | 956 (86.0) | 331 (69.8) | |
SRCC | 299 (18.9) | 156 (14.0) | 143 (30.2) | |
Borrmann classification | <0.001 | |||
Non-Borrmann IV | 1,420 (89.5) | 1,022 (91.9) | 398 (84.0) | |
Borrmann IV | 166 (10.5) | 90 (8.1) | 76 (16.0) | |
T stage | <0.001 | |||
1 | 118 (7.4) | 86 (7.7) | 32 (6.7) | |
2 | 174 (11.0) | 90 (8.1) | 84 (17.7) | |
3 | 321 (20.2) | 21 (1.9) | 300 (63.3) | |
4 | 973 (61.3) | 915 (82.3) | 58 (12.3) | |
N stage | <0.001 | |||
0 | 407 (25.7) | 260 (23.4) | 147 (31.0) | |
1 | 307 (19.4) | 189 (17.0) | 118 (24.9) | |
2 | 340 (21.4) | 213 (19.1) | 127 (26.8) | |
3a | 420 (26.5) | 338 (30.4) | 82 (17.3) | |
3b | 112 (7.1) | 112 (10.1) | 0 (0) | |
Peritoneal dissemination | <0.001 | |||
No | 1,271 (80.1) | 862 (77.5) | 409 (86.3) | |
Yes | 315 (19.9) | 250 (22.5) | 65 (13.7) |