2. Clinicopathological factors associated with peritoneal dissemination in patients with gastric cancer (Development set, n=1,112).
Variables | Peritoneal dissemination [n (%)] | Univariate analysis | Multivariable analysis | ||||
Positive | Negative | P | OR (95% CI) | P | |||
SRCC, signet-ring cell carcinoma; CEA, carcinoembryonic antigen; OR, odds ratio; 95% CI, 95% confidence interval. | |||||||
Sex | 0.001 | 1.416 (1.019−1.967) | 0.038 | ||||
Male | 146 (58.4) | 605 (70.2) | |||||
Female | 104 (41.6) | 257 (29.8) | |||||
Age (year) | <0.001 | 0.597 (0.434−0.821) | 0.002 | ||||
<55 | 135 (54.0) | 311 (36.1) | |||||
≥55 | 115 (46.0) | 551 (63.9) | |||||
Tumor location | <0.001 | 1.213 (1.034−1.424) | 0.018 | ||||
Proximal | 57 (22.8) | 366 (42.5) | |||||
Middle | 75 (30.0) | 154 (17.9) | |||||
Distal | 113 (45.2) | 302 (35.0) | |||||
Entire | 3 (1.2) | 13 (1.5) | |||||
Residual | 2 (0.8) | 27 (3.1) | |||||
Tumor size (cm) | <0.001 | 2.387 (1.718−3.317) | <0.001 | ||||
≤5 | 100 (40.0) | 555 (64.4) | |||||
>5 | 150 (60.0) | 307 (35.6) | |||||
Pathological type | <0.001 | 2.923 (1.968−4.341) | <0.001 | ||||
SRCC | 76 (30.4) | 80 (9.3) | |||||
Non-SRCC | 174 (69.6) | 782 (90.7) | |||||
Borrmann classification | <0.001 | 3.210 (1.842−5.594) | <0.001 | ||||
Borrmann IV | 47 (18.8) | 43 (5.0) | |||||
Non-Borrmann IV | 203 (81.2) | 819 (95.0) | |||||
CEA (ng/mL) | 0.093 | ||||||
<5 | 200 (80.0) | 643 (74.6) | |||||
≥5 | 50 (20.0) | 219 (25.4) | |||||
T stage | 0.024 | 1.592 (1.282−1.977) | <0.001 | ||||
1 | 12 (4.8) | 74 (8.6) | |||||
2 | 12 (4.8) | 78 (9.0) | |||||
3 | 5 (2.0) | 16 (1.9) | |||||
4 | 221 (88.4) | 694 (80.5) | |||||
N stage | <0.001 | 1.461 (1.288−1.658) | <0.001 | ||||
0 | 16 (6.4) | 244 (28.3) | |||||
1 | 32 (12.8) | 157 (18.2) | |||||
2 | 42 (16.8) | 171 (19.8) | |||||
3a | 143 (57.2) | 195 (22.6) | |||||
3b | 17 (6.8) | 95 (11.0) |