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. 2020 May 7;3(6):e201900545. doi: 10.26508/lsa.201900545

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© 2020 Ngan et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure S10. — Immunohistochemistry staining of tumor infiltrating lymphocytes in in-house HNSCC tumors. (A) Immunohistochemical staining of two additional pairs of head and neck squamous cell carcinoma (HNSCC) tumors (MAPK pathway-mutated versus WT), showing increases in the levels of intratumoral infiltrations of CD8⁺ T-cells, dendritic cells, and neutrophils. T25 (MAPK-mutated HNSCC tumor with bearing HRAS p.G12S and MAPK1 p.R135K) versus T75 (MAPK-WT) and T06 (MAPK-mutated HNSCC tumors with HRAS p.G13D mutation) versus T39 (MAPK-WT). Scale bars of 100 μm are shown. (B) The corresponding isotype control stainings of MAPK-mutated T40, T25, and T06 as well as MAPK-WT T69, T75, and T39 are shown. Scale bars of 100 μm are shown.