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. 2020 May 7;3(6):e201900545. doi: 10.26508/lsa.201900545

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© 2020 Ngan et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure S14. — OS prediction by TMB in HNSCC immunotherapy cohorts. (A) Kaplan–Meier overall survival curves for tumor mutational burden (TMB)-high versus TMB-low patients (study by Samstein et al (2019); HNSCC Oral subsite cohort; N = 47). (B) In HNSCC patients with distant metastases (lung, liver, heart, brain, and bone), TMB-high (defined by TMB value >10.3 for head and neck cancer from Samstein et al (2019)) is also associated with improved overall survival (P = 0.1969, a trend; right panel).