Figure 7.

B4Crry inhibited long-term complement C3d deposition on perilesional synapses. A, IF staining for C3d deposition in synapses within zone 2 of each of the three groups. Iba1, magenta; SV-2, blue; C3d, yellow. B, Quantification of C3d deposition and number of C3d⁺ synapses in high-power fields from the different treatment groups (blue, vehicle; red, t-PA; magenta, B4Crry+t-PA). ANOVA with Bonferroni. N = 5/group; *p < 0.05, **p < 0.01. Bars = mean ± SEM. All pairwise comparisons were performed, and only significant results are highlighted with *.