Table 1. Characteristics at screening for all enrolled male subjects.
Data are presented as the number (%) or median (interquartile range).
| Antioxidants (n=85) | Placebo (n=86) | |
|---|---|---|
| Age (years) | 34.0 (30.0, 38.0) | 34.0 (30.0, 37.0) |
| Body mass index (kg/m2) | 27.8 (24.2, 31.7), n=82 | 27.6 (24.4, 31.0) |
| Ethnicity | ||
| Hispanic or Latino | 7 (8.2) | 5 (5.8) |
| Non-Hispanic | 72 (84.7) | 78 (90.7) |
| Unknown | 6 (7.1) | 3 (3.5) |
| Race | ||
| White | 63 (74.1) | 69 (80.2) |
| Black | 6 (7.1) | 7 (8.1) |
| Asian | 7 (8.2) | 2 (2.3) |
| American Indian or Alaska Native | 1 (12) | 1 (12) |
| Unknown | 8 (9.4) | 5 (5.8) |
| Mixed Race | 0 (0) | 2 (2.3) |
| Abnormal semen parameters | ||
| Single abnormal parameter | ||
| Sperm concentration ≤15 Million/ml | 4 (4.7) | 5 (5.8) |
| Total motility ≤40% | 9 (10.6) | 10 (11.6) |
| Normal morphology# ≤4% | 33 (38.8) | 29 (33.7) |
| >1 abnormal parameters | 39 (45.9) | 42 (48.8) |
| Fathered a prior pregnancy^ | ||
| Yes | 25 (29.4) | 38 (44.2) |
| No | 60 (70.6) | 48 (55.8) |
| Prior infertility treatment and/or surgery | ||
| Yes | 25 (29.4) | 24 (27.9) |
| No | 60 (70.6) | 62 (72.1) |
| Duration of infertility (months) | 24.0 (18.0, 48.0), n=81 | 24.0 (15.0, 36.0), n=83 |
| History of smoking | ||
| Never | 54 (63.5) | 47 (54.7) |
| Current | 8 (9.4) | 11 (12.8) |
| Former | 23 (27.1) | 28 (32.6) |
| History of alcohol use | ||
| Never | 6 (7.1) | 4 (4.7) |
| Current (in the past year) | 72 (84.7) | 81 (94.2) |
| Former (not in the past year) | 7 (8.2) | 1 (12) |
#
WHO 5th criteria.
^
p<0.05, Wilcoxon’s rank-sum test was used for the continuous variables, and Chi-square or Fisher’s exact test was used for categorical variables. Wilcoxon’s rank-sum test was used to test the distributional difference, instead of mean or median of the two groups