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. Author manuscript; available in PMC: 2020 Nov 26.

Published in final edited form as: Circulation. 2019 Oct 4;140(22):1820–1833. doi: 10.1161/CIRCULATIONAHA.119.040740

Figure 2. — 5-month-old KO and WT mice were examined by transthoracic echocardiogram. A. Ejection fraction (EF). B. Fractional shortening (FS). C. Left ventricle internal dimension at end-diastole (LVID; d). D. Left ventricle internal dimension at end-systole (LVID; s). E. Left ventricle posterior wall thickness at end-diastole (LVPW; d). F. Left ventricle posterior wall thickness at end-systole (LVPW; s). G. Heart weight. H. Heart weight normalized by tibia length (HW/TL). I. Body weight. J. Body composition: muscle weight and fat weight was measured by Nuclear Magnetic Resonance analyzer. The percentage of muscle weight and fat weight was then calculated by dividing the muscle or fat weight by body weight. n=4–7 per group. * p<0.05, Mann-Whitney test.

Figure 2. — 5-month-old KO and WT mice were examined by transthoracic echocardiogram. A. Ejection fraction (EF). B. Fractional shortening (FS). C. Left ventricle internal dimension at end-diastole (LVID; d). D. Left ventricle internal dimension at end-systole (LVID; s). E. Left ventricle posterior wall thickness at end-diastole (LVPW; d). F. Left ventricle posterior wall thickness at end-systole (LVPW; s). G. Heart weight. H. Heart weight normalized by tibia length (HW/TL). I. Body weight. J. Body composition: muscle weight and fat weight was measured by Nuclear Magnetic Resonance analyzer. The percentage of muscle weight and fat weight was then calculated by dividing the muscle or fat weight by body weight. n=4–7 per group. * p<0.05, Mann-Whitney test.