Evaluation of cwp22 mutation on C. difficile virulence in mice.
A. Mean relative weight changes.
B. Survival curves.
C. Diarrhoea percentages.
D. C. difficile in faeces.
E. C. difficile in cecum at postchallenge day 7.
F. Toxin titre of faecal samples. Bars stand for mean ± SEM (*P < 0.05). One-way ANOVA was used for statistical significance. Animal survivals were analysed by Kaplan–Meier survival analysis with a log-rank test of significance.