Skip to main content
. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Stroke. 2020 Jan 8;51(2):372–378. doi: 10.1161/STROKEAHA.119.025139

Table 2.

Associations Between Pulse Pressure (PP) and Mean Arterial Pressure (MAP) at Study Entry and Regional White Matter Hyperintensity Volume at MRI Visit

Beta LCL UCL

Frontal      
 PP (z-score) 1.014 −3.207 5.419
 MAP (z-score) 6.670 2.293 11.233
Parietal      
 PP (z-score) −1.097 −5.230 3.215
 MAP (z-score) 4.787 0.488 9.271
Temporal      
 PP (z-score) 1.671 −2.577 6.105
 MAP (z-score) 1.408 −2.752 5.747
Anterior PV      
 PP (z-score) 0.728 −3.481 5.120
 MAP (z-score) 10.909 6.359 15.654
Posterior PV      
 PP (z-score) 0.130 −4.054 4.496
 MAP (z-score) 7.681 3.263 12.288
Occipital      
 PP (z-score) 0.674 −3.197 4.700
 MAP (z-score) 2.219 −1.645 6.235

PP=pulse pressure and MAP=mean arterial pressure. PP and MAP expressed as z-score units. Estimates are transformed such that they represent the expected percent change in WMHV per z-score unit of PP and MAP. Model adjusted for age, sex, race/ethnicity, TIV, BMI, brain region, smoking status, anti-hypertensive medication use, any physical activity, moderate alcohol consumption, diabetes, hyperlipidemia, years between baseline and MRI, and two-way multiplicative interaction terms between brain region and age, sex, race/ethnicity, TIV, anti-hypertensive medication use, smoking status, diabetes, and years between baseline and MRI.