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. 2020 May 13;15(5):e0232457. doi: 10.1371/journal.pone.0232457

Fig 4. Evidence supports PP interval more than 1.5 seconds as a criterion to define a Sinus Arrest (SA) episode in adult zebrafish.

Fig 4

A, Summary of electrocardiographic (ECG) data from 59 wild-type (WT) and 16 Tg(SCN5A-D1275N) fish at 1 year old. Different cut-offs of PP intervals were used to determine an episode of SA. B, Two wild-type (WT) fish and 3 Tg(SCN5A-D1275N) fish that were considered to have SA when 1.2 seconds was used as cut-off, but not if 1.6 seconds was used as cut-off, were further analyzed by reviewing the raw ECG. We considered WT fish 1 and 2 and Tg fish 2 as SA-positive, and others were not because of low frequency of long PP interval. An PP interval more than 1.5 seconds was recommended as a criterion to define SA in zebrafish. C, Representative SA episodes in a WT fish and a Tg(SCN5A-D1275N) fish. epm indicates episodes per minute.