Table 4. Clinicopathologic features and distribution of CAV1 and ATG4C in cancer cells of 95 epithelial ovarian cancer patients.
| Parameters | N | CAV1 | ATG4C | ||||
|---|---|---|---|---|---|---|---|
| Low (%) | High (%) | P value | Low (%) | High (%) | P value | ||
| Age | 0.521 | 0.690 | |||||
| <60 years | 77 | 32(33.7) | 45(47.4) | 22(23.2) | 55(57.9) | ||
| ≧60 years | 18 | 6(6.3) | 12(12.6) | 6(6.3) | 12(12.6) | ||
| Histologic subtype | 0.870 | 0.005* | |||||
| Serous | 47 | 19(20.0) | 28(29.4) | 7(7.4) | 40(42.1) | ||
| Clear cell | 1 | 0(0.0) | 1(1.1) | 0(0.0) | 1(1.1) | ||
| Mucinous | 17 | 8(8.4) | 9(9.5) | 6(6.3) | 11(11.5) | ||
| Endometrioid | 30 | 11(11.6) | 19(20.0) | 15(15.8) | 15(15.8) | ||
| Histologic grade | 0.708 | 0.934 | |||||
| I | 21 | 10(10.5) | 11(11.6) | 6(6.3) | 15(15.8) | ||
| II | 28 | 11(11.6) | 17(17.9) | 9(9.5) | 19(20.0) | ||
| III | 46 | 17(17.9) | 29(30.5) | 13(13.7) | 33(34.7) | ||
| Tumor size (T) | 0.185 | 0.817 | |||||
| T1 | 47 | 20(21.2) | 27(28.4) | 14(14.8) | 33(34.8) | ||
| T2 | 24 | 6(6.3) | 18(18.9) | 8(8.4) | 16(16.8) | ||
| T3 | 24 | 12(12.6) | 12(12.6) | 6(6.3) | 18(18.9) | ||
| Lymph node metastasis (N) | 0.680 | 1.000 | |||||
| N0 | 89 | 35(36.8) | 54(56.8) | 26(27.4) | 63(66.3) | ||
| N1 | 6 | 3(3.2) | 3(3.2) | 2(2.1) | 4(4.2) | ||
| Distant metastasis (M) | 0.189 | 0.519 | |||||
| M0 | 74 | 27(28.4) | 47(49.5) | 23(24.2) | 51(53.7) | ||
| M1 | 21 | 11(11.6) | 10(10.5) | 5(5.3) | 16(16.8) | ||
| FIGO stage | 0.185 | 0.817 | |||||
| I | 47 | 20(21.1) | 27(28.5) | 14(14.8) | 33(34.8) | ||
| II | 24 | 6(6.3) | 18(18.9) | 8(8.4) | 16(16.8) | ||
| III/IV | 24 | 12(12.6) | 12(12.6) | 6(6.3) | 18(18.9) | ||
Data were expressed as count and percentage for categorical variables and analyzed by Chi-square test, Continuity correction, or Fisher’s exact test.
*indicates that the difference was statistically significant.