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. Author manuscript; available in PMC: 2020 May 13.
Published in final edited form as: Ann Pancreat Cancer. 2019 Dec;2:21. doi: 10.21037/apc.2019.11.01

Figure 2.

Figure 2

Administering combination immunotherapy after gemcitabine improves the infiltration of IFN-γ-expressing CD8+ T-cells into PDA. (A) After receiving 2 weeks of therapy, the KPC tumor-bearing mice were sacrificed (on day 18), and the liver metastasis-infiltrating CD8+ T-cells were analyzed with flow cytometry. The number of (B) CD8+ T-cells and (C) INF-γ-expressing CD8+ T-cells; (D) the percentage of CD8+ T-cells that expressed INF-γ. N=4 mice per treatment group. **, P<0.01; ****, P<0.0001. Data represents mean ± standard deviation. The experiment was performed once.