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. 2019 Jul 15;11(3):547–558. doi: 10.14336/AD.2019.0715

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Copyright: © 2019 Shimizu et al.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 3. — Immunohistochemical detection of human esRAGE. A) Immunohistochemical study for the detection of human esRAGE (green signals). Hippocampal vasculatures and CA1 regions of WT side of WT→WT and esRAGE Tg (Tg)→WT pairs, the Tg side of the WT→Tg pair, and the RAGE knockout (KO) side of the Tg→KO pair without BCCAO. B) Immunostaining for NeuN (a neuronal marker, green) and human esRAGE (red) (left panel) as well as GFAP (a glial marker, green) and human esRAGE (red) (right panel) in brain cortex and hippocampus of WT sides of Tg→WT pair. Blue signals indicate nuclei [4',6-diamidino-2-phenylindole (DAPI) stain].