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. 2019 Jul 15;11(3):547–558. doi: 10.14336/AD.2019.0715

Figure 5.

Figure 5.

Association of esRAGE with endothelial cells. A and B) Immunofluorescence studies of human brain endothelial cells (HBEC) in culture. Green, Red and blue signals indicate esRAGE, heparin sulfate and nucleus (DAPI), respectively. Bar, 50 µm. C) Human esRAGE levels in culture media of HBEC (n = 4). esRAGE, 1 µg/ml; Heparin, 0.1 IU/ml; heparitinase, 1 mU/ml. Values are mean ± SEM. C) Serum levels of human esRAGE in the esRAGE Tg mice with or without heparin injection (n = 4-8). Values are mean ± SEM.