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. Author manuscript; available in PMC: 2020 May 14.
Published in final edited form as: J Am Chem Soc. 2019 Dec 6;141(50):19677–19687. doi: 10.1021/jacs.9b07883

Fig. 7.

Fig. 7

Thermal denaturation profiles of MOR (a) and resulting melting temperature (Tm) of the receptor in TSMs (TSM-E9/E10/T8/T9) and TEMs (TEM-E9/E10/T8/T9). DDM and LMNG were used to compare detergent efficacy. Temperature varied from 20 to 65 °C. Tm of the receptor was obtained via CPM assay using the detergents at 0.5 wt%. Due to protein instability, CPM assay with the DDM-solubilized receptor was carried out without detergent exchange. Error bars, SEM; n = 2-3.