Table 1.
Characteristics of Helicobacter pylori testing among 35 patients with H. pylori positive gastric cancer and 56 patients with H. pylori negative gastric cancer. Additional comparison included 26 patients with suspected H. pylori gastric cancer (i.e., atrophic gastritis or gastric intestinal metaplasia on gastric biopsy in the setting of negative H. pylori testing).
| H. pylori Positive Gastric Cancer (n=35) | H. pylori Negative Gastric Cancer (n=56) | p-value | H. pylori Positive Gastric Cancer (including suspected) (n=61) | H. pylori Negative Gastric Cancer (excluding suspected) (n=30) | p-value | |
|---|---|---|---|---|---|---|
| Histopathology of non-cancer gastric biopsy without special stain | 14 (40.0) | 11 (19.6) | 0.034 | 20 (32.8) | 5 (16.7) | 0.136 |
| Histopathology of non-cancer gastric biopsy with special stain | 14 (40.0) | 24 (42.9) | 0.788 | 31 (50.8) | 7 (23.3) | 0.014 |
| H. pylori IgG serology | 20 (57.1) | 14 (25.0) | 0.002 | 26 (42.6) | 8 (26.7) | 0.139 |
| H. pylori stool antigen | 0 (0.0) | 1 (1.8) | --- | 0 (0.0) | 1 (3.3) | 0.330 |
| 1 test for H. pylori (meaning gastric cancer biopsy only) | 1 (2.9) | 16 (28.6) | 0.002 | 3 (4.9) | 14 (46.7) | <0.001 |
| ≥2 tests for H. pylori | 34 (97.1) | 40 (71.4) | 0.181 | 58 (95.1) | 16 (53.3) | 0.425 |
| ≥3 tests for H. pylori | 14 (40.0) | 9 (16.1) | 0.624 | 19 (31.1) | 4 (13.3) | 0.765 |