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Reaction rate constants for rocR-mediated CDNs cleavage[a]
|
k1 (μM−1s−1) |
k−1 (s−1) |
k2 (s−1) |
k3 (μM−1s−1) |
k−3 (s−1) |
k4 (s−1) |
|
|---|---|---|---|---|---|---|
| c-di-GMP | 3.96 ± 0.07 | 1.15 ± 0.21 | 0.76 ± 0.03 | NA | NA | NA |
| c-di-tzGMP | 0.043 ± 0.02 | 0.09n± 0.07 | 0.83 ± 0.55 | NA | NA | NA |
| c-GthGMP | 0.021 ± 0.001 | 0.033 ± 0.001 | 5 ± 0.57 | NA | NA | NA |
| c-GtzGMP | 1.85 ± 0.07 | 0.096 ± 0.091 | 3.07 ± 0.25 | 1.8 ± 0.1 | 0.135 ± 0.007 | 0.34 ± 0.01 |
Data were presented as mean ± SD.
