Table 1.

Phyla and genera differences in gut microbial populations shown in actual reads and relative abundance

	Cellulose + Vehicle		Cellulose + PCB 126		Inulin + Vehicle		Inulin + PCB 126
Phyla	Actual Reads	Relative Abundance(%)	Actual Reads	Relative Abundance (%)	Actual Reads	Relative Abundance (%)	Actual Reads	Relative Abundance (%)
Actinobacteria#	17.8 ± 3.2	0.02 ± 0.004	32.7 ± 9.8	0.04 ± 0.01	604.0 ± 137.4*	0.74 ± 0.18*	1443.2 ±197.5*‡	1.94 ± 0.25*‡
Bacteroidetes#	12730.8 ± 2468.6	15.35 ± 2.72	10020.2 ± 1636.8	13.23 ± 2.15	28962.1 ± 1983.8*	36.97 ± 4.17*	15946.7 ± 1894.5‡	21.70 ± 2.59‡
Firmicutes#	28488.4 ± 2974.5	34.02 ± 1.99	22729.7 ± 1972.2	29.48 ± 2.31	20001.8 ± 2243.2	27.48 ± 3.49	24398.2 ± 2434.9	32.04 ± 1.92
Proteobacteria$@	2920.3 ± 706.1	3.47 ± 0.89	1364.4 ±246.8‡	1.80 ± 0.33‡	1599.3 ± 134.6	2.15 ± 0.24	1013.8 ±133.3	1.37 ± 0.18
Tenericutes#	83.0 ± 40.1	0.09 ± 0.04	137.9 ±37.5	0.19 ± 0.05	203.7 ± 48.0	0.27 ± 0.07	78.8 ± 23.2	0.10 ± 0.03
Verrucomicrobia$@	37404.8 ± 2784.3	46.59 ± 3.55	43083.4 ± 3849.8	54.95 ± 3.07	21070.8 ± 2235.6*	31.68 ± 3.91*	31417.9 ± 2044.9‡	41.79 ± 1.21‡
Genera	Actual Reads	Relative Abundance(%)	Actual Reads	Relative Abundance (%)	Actual Reads	Relative Abundance (%)	Actual Reads	Relative Abundance (%)
Bifidobacterium#	12.1 ± 3.0	0.02 ± 0.003	24.1 ± 9.7	0.03 ± 0.01	597.2 ± 136.7*	0.66 ± 0.18*	1432.5 ± 196.6*‡	1.92 ± 0.25*‡
Lactobacillus#	19.8 ± 6.7	0.03 ± 0.01	13.1 ± 4.8	0.02 ± 0.01	152.1 ± 41.9*	0.17 ± 0.06*	403.1 ± 95.9*‡	0.51 ± 0.09*‡
Lactococcus-	219.6 ± 42.7	0.27 ± 0.05	212.1 ± 72.4	0.26 ± 0.08	123.7 ± 19.5	0.17 ± 0.03	161.3 ± 31.3	0.23 ± 0.04
Turicibactef#	38.5 ± 10.4	0.05 ± 0.01	11.7 ± 3.0‡	0.01 ± 0.003‡	3.6 ± 0.8*	0.01 ± 0.001*	3.9 ± 1.3	0.005 ± 0.001
Clostridium$	18.4 ± 4.3	0.02 ± 0.004	19.6 ± 2.9	0.03 ± 0.004	4.2 ± 1.4*	0.01 ± 0.002*	2.5 ± 0.7*	0.004 ± 0.001*
Dehalobacterium@	74.2 ± 8.8	0.09 ± 0.01	43.9 ± 7.7	0.06 ± 0.01	88.3 ± 23.2	0.10 ± 0.03	46.3 ± 7.9	0.06 ± 0.01
Coprococcus#	302.0 ± 38.0	0.36 ± 0.04	863.6 ± 234.4‡	1.09 ± 0.26‡	61.9 ± 21.0*	0.19 ± 0.03*	108.7 ± 23.5	0.14 ± 0.02
Dorea#	126.0 ±14.7	0.16 ± 0.02	41.2 ± 13.4‡	0.05 ± 0.02‡	21.3 ± 8.2*	0.03 ± 0.01*	16.4 ± 4.7*	0.02 ± 0.01*
[Ruminococcus]#	462.0 ± 58.0	0.55 ± 0.04	560.4 ± 35.1	0.72 ± 0.05	129.0 ± 16.3	0.22 ± 0.03	908.0 ± 193.5‡	1.28 ± 0.29‡
rc4–4#	1405.0 ± 409.1	1.66 ± 0.44	0.8 ± 0.5‡	0.001 ± 0.0004‡	211.0 ± 96.1*	0.23 ± 0.13*	249.0 ± 44.9*	0.33 ± 0.05*
Oscillospira$@	2755.2 ± 352.2	3.26 ± 0.25	1784.1 ± 214.2‡	2.27 ± 0.21‡	1251.0 ± 215.7*	1.64 ± 0.32*	1115.0 ± 118.4	1.53 ± 0.19
Ruminococcus#	727.4 ± 63.9	0.89 ± 0.06	861.8 ± 85.1	1.12 ± 0.10	545.6 ± 75.5	0.73 ± 0.12	340.8 ± 58.4*	0.45 ± 0.07*
Allobaculum#	5064.8 ± 1593.3	5.92 ±1.74	2007.5 ± 565.8	2.64 ± 0.77	12019.1 ± 2319.5*	13.59 ± 3.05	14419.7 ± 1895.7*	18.66 ± 1.52*
Coprobacillus$	66.9 ± 14.2	0.08 ± 0.02	82.8 ± 16.1	0.11 ± 0.02	1.0 ± 0.5*	0.01 ± 0.002*	2.8 ± 1.0*	0.004 ± 0.001*
Sutterella#	772.2 ± 295.0	0.90 + 0.35	1092.1 ± 178.2	1.46 + 0.26	1585.3 ± 135.0*	1.93 ± 0.25*	993.7 ± 133.1	1.35 ± 0.17
Desulfovibrio#	2129.3± 811.1	2.55 + 1.01	6.2 ± 1.4‡	0.008 + 0.001‡	2.6 ± 0.8*	0.004 ± 0.001*	7.6 ± 3.6	0.01 ± 0.003
Akkermansia$@	37403.2 ± 2784.1	46.59 + 3.55	43081.5 ± 3849.6	54.94 + 3.07	21070.1 ± 2235.5*	31.68 ± 3.91*	31416.8 ± 2044.5‡	41.79 ± 1.21‡

Phyla and genera displayed are those with consistent quantifiable reads. Phyla classified as “other” were not included in the table.

^*indicates a significant difference compared to cellulose diet of same treatment;

^‡indicates a significant difference compared to vehicle of same diet (n=10).

^$indicates a significant diet effect,

^@indicates a significant exposure,

^#indicates a significant interaction between diet and exposure. Data analyzed by two-way ANOVA with post hoc comparisons of the means.