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. 2020 May 13;10:7901. doi: 10.1038/s41598-020-64788-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Survival and function analysis of neutrophils after IFN-γ stimulus. Neutrophils from C57BL/6 (WT) and Sting^−/− mice were stimulated with 200 ng/μL of IFN-γ for survival evaluation (n = 5) (a). Soluble adult worm antigen (SWAP), medium, and lipopolysaccharide (LPS) were used as experimental controls. Additionally, we determine neutrophils ability to kill 100 schistosomula in vitro (n = 5) (b). (*) or (**) or (***) or (****) are used to demonstrate statistical differences at p < 0.05 or p < 0.01 or p < 0.001 or p < 0.0001, respectively. One-Way (b) or Two-Way (a) ANOVA with Bonferroni adjustments were included for multiple comparisons.