Table 3. Independent risk factors of end-stage renal disease (ESRD), long-term mortality, and composite endpoints among the overall study cohort.
AHR for ESRD (95% C.I.) | AHR for death (95% C.I.) | AHR for composite endpoint (95% C.I.) | |
Male (vs. female) | 1.66 (0.62, 4.41) | 0.78 (0.56, 1.08) | 0.79 (0.57, 1.08) |
Age (per 10 years) | 0.65 (0.41, 1.04) | 1.57 (1.34, 1.84)† | 1.43 (1.23, 1.66)† |
eGFR (per 10 units) | 0.25 (0.14, 0.43)† | 0.96 (0.88, 1.04) | 0.89 (0.82, 0.97)# |
AKI | 2.79 (0.75, 10.33) | 6.63 (4.31, 10.20)† | 6.19 (4.06, 9.42)† |
DM | 8.81 (1.14, 68.08)* | 1.57 (1.13, 2.18)# | 1.69 (1.23, 2.33)# |
Hypertension | 5.15 (0.64, 41.73) | 0.96 (0.65, 1.40) | 1.04 (0.71, 1.51) |
Dyslipidemia | 1.02 (0.37, 2.83) | 0.74 (0.54, 1.00)* | 0.79 (0.59, 1.05) |
Prior CAD | 0.55 (0.21, 1.45) | 1.26 (0.90, 1.77) | 1.20 (0.87, 1.66) |
Prior CHF | 1.38 (0.45, 4.19) | 1.67 (1.16, 2.42)# | 1.56 (1.10, 2.22)* |
Prior CVD | 1.00 (0.32, 3.14) | 1.62 (1.13, 2.33)# | 1.59 (1.12, 2.27)# |
Prior PVD | 0.63 (0.07, 5.52) | 1.01 (0.49, 2.07) | 0.92 (0.45, 1.89) |
Prior CLD | 0.85 (0.10, 7.47) | 1.10 (0.62, 1.93) | 1.16 (0.67, 1.99) |
AMI (vs. non-AMI) | 0.29 (0.10, 0.81)* | 1.23 (0.89, 1.70) | 1.09 (0.80, 1.49) |
AHR, adjusted hazard ratios; AKI, acute kidney injury; AMI, acute myocardial infarction; CAD, coronary artery disease; CHF, congestive heart failure; CLD, chronic lung disease; CVD, cerebrovascular disease; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate (ml/min/1.73 m2); PVD, peripheral vascular disease; 95% C.I., 95% confidence interval.
* p < 0.05; # p < 0.01; † p < 0.001.