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Table 3. Independent risk factors of end-stage renal disease (ESRD), long-term mortality, and composite endpoints among the overall study cohort.

AHR for ESRD (95% C.I.) AHR for death (95% C.I.) AHR for composite endpoint (95% C.I.)
Male (vs. female) 1.66 (0.62, 4.41) 0.78 (0.56, 1.08) 0.79 (0.57, 1.08)
Age (per 10 years) 0.65 (0.41, 1.04) 1.57 (1.34, 1.84) 1.43 (1.23, 1.66)
eGFR (per 10 units) 0.25 (0.14, 0.43) 0.96 (0.88, 1.04) 0.89 (0.82, 0.97)#
AKI 2.79 (0.75, 10.33) 6.63 (4.31, 10.20) 6.19 (4.06, 9.42)
DM 8.81 (1.14, 68.08)* 1.57 (1.13, 2.18)# 1.69 (1.23, 2.33)#
Hypertension 5.15 (0.64, 41.73) 0.96 (0.65, 1.40) 1.04 (0.71, 1.51)
Dyslipidemia 1.02 (0.37, 2.83) 0.74 (0.54, 1.00)* 0.79 (0.59, 1.05)
Prior CAD 0.55 (0.21, 1.45) 1.26 (0.90, 1.77) 1.20 (0.87, 1.66)
Prior CHF 1.38 (0.45, 4.19) 1.67 (1.16, 2.42)# 1.56 (1.10, 2.22)*
Prior CVD 1.00 (0.32, 3.14) 1.62 (1.13, 2.33)# 1.59 (1.12, 2.27)#
Prior PVD 0.63 (0.07, 5.52) 1.01 (0.49, 2.07) 0.92 (0.45, 1.89)
Prior CLD 0.85 (0.10, 7.47) 1.10 (0.62, 1.93) 1.16 (0.67, 1.99)
AMI (vs. non-AMI) 0.29 (0.10, 0.81)* 1.23 (0.89, 1.70) 1.09 (0.80, 1.49)

AHR, adjusted hazard ratios; AKI, acute kidney injury; AMI, acute myocardial infarction; CAD, coronary artery disease; CHF, congestive heart failure; CLD, chronic lung disease; CVD, cerebrovascular disease; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate (ml/min/1.73 m2); PVD, peripheral vascular disease; 95% C.I., 95% confidence interval.

* p < 0.05; # p < 0.01; p < 0.001.