ACE2, renin-angiotensin system, SARS-CoV-2 and COVID-19. ACE, angiotensin-converting enzyme; ADAM17, a disintegrin and metalloproteinase 17; Ang, angiotensin; ARB, angiotensin receptor blocker; ARNI, angiotensin receptor neprilysin inhibitor; AT1R, angiotensin 1 receptor; COVID-19, coronavirus disease 2019; SARS-CoV-2, severe adult respiratory syndrome coronavirus-2; TMPRSS2, transmembrane protease serine 2.