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Table 1. Clinical characteristics of the study groups.

Normal (n = 50) CAD (n = 50) CAE (n = 40) p value
Age (years) 58.06 ± 9.51 62.08 ± 8.29 61.28 ± 8.46 0.510
Gender (M), n (%) 15 (21.4%) 29 (41.4%) 26 (37.1%) 0.002
BMI (kg/m2) 25.02 ± 1.63 25.50 ± 2.38 25.17 ± 1.48 0.232
DM, n (%) 11 (26.2%) 19 (45.2%) 12 (28.6%) 0.201
Hypertension, n (%) 30 (33.3%) 32 (35.6%) 28 (32.1%) 0.615
Alcohol, n (%) 18 (33.3%) 19 (35.2%) 17 (31.5%) 0.156
Smoking, n (%) 16 (33.3%) 17 (35.4%) 15 (31.3%) 0.860
Family history of CAD, n (%) 14 (32.6%) 19 (44.2%) 10 (23.3%) 0.126
Previous medications
 Aspirin, n (%) 18 (28.6%) 23 (36.5%) 22 (34.9%) 0.195
 b-blocker, n (%) 32 (35.2%) 36 (39.6%) 23 (25.3%) 0.352
 CCB, n (%) 12 (28.6%) 16 (38.1%) 14 (33.3%) 0.490
 ACEI/ARB, n (%) 26 (36.6%) 21 (29.6%) 24 (33.8%) 0.231
Statin, n (%)
Hypoglycemic agents, n (%) 8 (28.6%) 11 (39.3%) 9 (32.4%) 0.677

ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin receptor blocker; BMI, body mass index; CAD, coronary artery disease; CCB, calcium channel blockers; DM, diabetes mellitus.