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. 2020 May 6;181(3):499–518. doi: 10.1007/s10549-020-05657-8

Table 1.

Characteristics of selected studies (n = 41)

Characteristics n % References
Country
 The Netherlands 13 31.7 [4050, 60, 65]
 Italy 8 19.5 [38, 39, 52, 55, 57, 58, 61, 66]
 Germany1 6 14.6 [12, 13, 2031, 36, 62, 64, 67, 68]
 France1 6 14.6 [3335, 51, 63, 69, 70]
 UK 4 9.8 [53, 54, 56, 71]
 Denmark 2 4.9 [72, 73]
 Croatia 1 2.4 [37]
 Belgium 1 2.4 [74]
Study design
 Retrospective cohort1 19 46.3 [13, 2527, 36, 40, 41, 4451, 57, 62, 66, 71, 73]
 Cross-sectional 13 31.7 [3739, 42, 5255, 58, 6365, 70]
 Non-controlled before-after 5 12.2 [35, 5961, 69]
 Prospective cohort1 2 4.9 [2931, 74]
 Case study1 1 2.4 [3234]
 Other (qualitative) 1 2.4 [56]
Publication yeara
 1999–2008 12 21.1 [35, 38, 39, 41, 45, 46, 52, 53, 60, 69, 71]
 2009–2011 13 22.8 [13, 21, 24, 25, 32, 40, 50, 51, 58, 6366]
 2012–2014 11 19.3 [12, 22, 26, 33, 34, 42, 48, 55, 61, 68, 70]
 2015–2017 16 28.1 [20, 23, 27, 28, 30, 31, 43, 44, 47, 49, 56, 59, 62, 67, 72, 74]
 2018–2019 5 8.8 [29, 36, 37, 54, 73]
Guideline scopeb
 Treatment1 31 75.6 [12, 13, 2030, 32, 35, 36, 40, 41, 4345, 47, 48, 50, 51, 5764, 66, 68, 69, 7174]
 Follow-up 4 9.8 [35, 42, 55, 57, 58, 69]
 Preventive measures 4 9.8 [37, 49, 53, 56, 70, 74]
 Diagnosis 4 9.8 [35, 58, 61, 65]
Risk of biasc
 Low 25 62.5 [13, 30, 35, 36, 4044, 46, 48, 49, 5558, 61, 65, 66, 7072, 74, 75]
 Moderate 14 35.0 [3739, 45, 47, 5054, 59, 60, 63, 69]
 High 1 2.5 [64]

1Reported in more than one separate publications

aPercentages calculated over the total number of publications (n = 57)

bThe total exceeds 100% since some guidelines comprised more than one scope

cPercentages over 40 studies, a case study was not evaluated