Systemic rmIL-6 Administration Increases Blood Plasma Concentration of IL-6 and Body Temperature
(A) Blood plasma levels of IL-6 in pg/mL measured by ELISA in groups of at least six mice that received different doses of rmIL-6 or PBS. Error bar indicates SEM from three independent experiments. ∗∗p < 0.01, ∗∗∗∗p < 0.0001 using Student's t test. n = 6.
(B) Mice body temperature measured 1 h after the last rmIL-6 injection. Numbers over bars represent fold change over PBS group. Error bar indicates SEM from three independent experiments. ∗p < 0.05, ∗∗∗∗p < 0.0001 using Student's t test. n = 12 mice.