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. 2020 May 13;10:56. doi: 10.1186/s13613-020-00672-w

Table 2.

Factors affecting 30-day survival of ICU patients aged ≥ 80 years with SOFA ≥ 2 at admission, multivariate analysis

HR (95% CI) p value
A. Results of the Cox analysis considering all acutely admitted patients (n = 3869)
 Sepsis 0.99 (0.86–1.15) p = 0.9173
 Age (per 5-year increase) 1.16 (1.09–1.25) p < 0.0001
 Frailty: vulnerable vs. fit 1.16 (1–1.35) p = 0.0556
 Frailty: frail vs. fit 1.47 (1.31–1.66) p < 0.0001
 Male vs. female 1.16 (1.05–1.28) p = 0.0043
 SOFA score (per one-point increase) 1.13 (1.12–1.14) p < 0.0001
B. Results of the Cox analysis considering only acute patients admitted for sepsis (n = 493)
 Age (per 5-year increase) 1.33 (1.1–1.61) p = 0.0029
 Frailty: vulnerable vs. fit 1.54 (1.02–2.34) p = 0.0416
 Frailty: frail vs. fit 1.47 (1.07–2.02) p = 0.0182
 Male vs. female 1.12 (0.85–1.47) p = 0.4202
 SOFA score (per one-point increase) 1.13 (1.1–1.17) p < 0.0001
C. Results of the Cox analysis considering only acute patients admitted for other reason than sepsis (n = 3376)
 Age (per 5-year increase) 1.14 (1.06–1.23) p = 0.0005
 Frailty: vulnerable vs. fit 1.11 (0.95–1.31) p = 0.1939
 Frailty: frail vs. fit 1.48 (1.31–1.68) p < 0.0001
 Male vs. female 1.16 (1.04–1.3) p = 0.0064
 SOFA score (per one-point increase) 1.13 (1.12–1.14) p < 0.0001