Table 2.
Expression changes of ncRNA in cardiomyocytes treated with DOX.
| ncRNA | Changes | Targets | Experimental model | References |
|---|---|---|---|---|
| miR-15b | Upregulated | Bmpr1a, Gata4, Nkx2-5 | H9c2 rat cardiomyocyte | (57) |
| miR-23a | Upregulated | PGC-1α | Rat (Sprague–Dawley); Primary rat cardiomyocyte |
(58) |
| miR-29b | Downregulated | Bax | Rat (Wistar); Primary rat cardiomyocyte |
(59) |
| miR-30 | Downregulated | β1AR, β2AR, Giα-2, BNIP3L | Rat (Sprague–Dawley); primary rat cardiomyocyte; H9c2 rat cardiomyocyte |
(60) |
| miR-34a | Upregulated | Bcl-2, SIRT1 | Rat (Sprague–Dawley); H9c2 rat cardiomyocyte |
(61, 62) |
| miR-140 | Upregulated | Nrf2, SIRT2 | Rat (Sprague–Dawley); mice (C57BL/6); H9c2 rat cardiomyocyte |
(63) |
| miR-146a | Upregulated | ErBb4 | Mice (C57BL/6); primary rat cardiomyocyte | (64) |
| miR-212/132 | Overexpression1 | Fitm2, Sgk3, Rbfox1 | Mice (C57BL/6N); primary rat cardiomyocyte; human iPSC-derived cardiomyocyte |
(65) |
| miR-532 | Upregulated | ARC | Primary rat and mice cardiomyocyte | (66) |
| LINC00339 | Upregulated | miR-484 | Rat (Sprague–Dawley); primary rat cardiomyocyte; H9c2 rat cardiomyocyte |
(67) |
1
Adenovirus-mediated overexpression.