Table 3.
Functional connectivity differences derived from pain-network ROI to ROI analyses in older compared to younger groups.
| T(68) | p-unc | p-FDR | |
|---|---|---|---|
| Older > Younger | |||
| SI (L)—ACC | 3.38 | 0.0006 | 0.0076 |
| SI (L)—SII (R) | 3.29 | 0.0008 | 0.0100 |
| ACC—SI (R) | 2.57 | 0.0061 | 0.0394 |
| SI (L)—dlPFC (R) | 2.40 | 0.0095 | 0.0411 |
| Older < Younger | |||
| INS (R)—AMY (R) | −3.85 | 0.0001 | 0.0016 |
| INS (L)—ACC | −3.43 | 0.0005 | 0.0065 |
| AMY (R)—AMY (L) | −3.41 | 0.0005 | 0.0069 |
| AMY (R)—ACC | −3.01 | 0.0018 | 0.0116 |
| AMY (R)—INS (L) | −2.86 | 0.0028 | 0.0180 |
| PAG—THA (R) | −2.77 | 0.0036 | 0.0239 |
| AMY (R)—THA (R) | −2.76 | 0.0037 | 0.0239 |
| INS (R)—AMY (L) | −2.72 | 0.0041 | 0.0259 |
| INS (R)—ACC | −2.58 | 0.0060 | 0.0259 |
| PAG—THA (L) | −2.54 | 0.0066 | 0.0428 |
| AMY (L)—THA (L) | −2.45 | 0.0083 | 0.0360 |
| AMY (L)—THA (R) | −2.22 | 0.0147 | 0.0478 |
SI, primary somatosensory cortex; SII, secondary somatosensory cortex; ACC, anterior cingulate cortex; dlPFC, dorsolateral prefrontal cortex; INS, insula; AMY, amygdala; PAG, periaqueductal gray matter; THA, thalamus; p-unc, p-uncorrected; p-FDR, p-False Discovery Rate.