Table 2.
Tumor features and treatment strategies of included studies.
| First author, year | Pituitary adenoma ratio (%) | Tumor location | Reconstruction strategy | LD placement criteria | LD protocol | ||
|---|---|---|---|---|---|---|---|
| Anterior fossa |
Sellar/ suprasellar |
Posterior fossa | |||||
| Patel et al. (6) | NR | 26 | 114 | 10 | Multilayer reconstruction (NSF) | High-flow leakage | 10 ml/h for 3 days |
| Garcia-Navarro et al. (17) | 17.4% | NR | NR | NR | Multilayer reconstruction (NSF, gasket, fat, DuraSeal) | NR | 5 ml/h for 1–2 days |
| Ivan et al. (18) | 25.5% | 36 | 24 | 26 | Multilayer reconstruction (NSF, DuraGen, fat, DuraSeal) | NR | 10–20 ml/h for 3–5 days |
| Pereira et al. (19) | 75.3% | – | 250 | – | Multilayer reconstruction (NSF, DuraSeal) | Giant tumor, large suprasellar extension | NR |
| Caggiano et al. (20) | 67.7% | NR | NR | NR | Multilayer reconstruction (NSF, fat graft, fascia lata) | Extended approach | NR |
| Jonathan et al. (21) | 100.0% | – | 60 | – | Multilayer reconstruction | Randomized | Drain for 5 days |
| Zwagerman et.al. (13) | 11.8% | 35 | 84 | 50 | Multilayer reconstruction (NSF, fascia lata, fat graft) | Randomized | 10 ml/h for 3 days |
| Albarbi et al. (22) | 100.0% | – | 186 | – | Multilayer reconstruction (NSF) | High-flow leakage, intracranial hypertension, poor reconstruction | Drain for 2 days |
LD, lumbar drainage; NR, not report; NSF, nasoseptal flaps.