Table 3.
Subgroup analyses: intraoperative lumbar drainage in endoscopic endonasal skull base surgeries.
| Subgroup characteristics | Number of studies | Pooled OR (95% CI) | P | Heterogeneity | ||
|---|---|---|---|---|---|---|
| P | I2 | Chi2 | ||||
| Intraoperative CSF leaks | ||||||
| • High-flow leaks | 4 | 0.37 (0.17, 0.83) | 0.02 | 0.96 | 0% | 0.31 |
| Prospective vs. retrospective studies | ||||||
| • Prospective studies | 4 | 0.34 (0.15, 0.74) | 0.007 | 1.00 | 0% | 0.07 |
| • Retrospective studies | 4 | 1.68 (0.73, 3.90) | 0.22 | 0.37 | 6% | 3.18 |
| Tumor type | ||||||
| • Mixed | 3 | 0.57 (0.21, 1.52) | 0.26 | 0.25 | 29% | 2.81 |
| • Pituitary adenoma | 4 | 0.70 (0.19, 2.54) | 0.59 | 0.21 | 33% | 4.50 |
OR, odds ratio; CI, confident interval; RCTs, randomized controlled trials.