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. 2020 May 7;11:801. doi: 10.3389/fimmu.2020.00801

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Copyright © 2020 Zuurveld, van Witzenburg, Garssen, Folkerts, Stahl, van't Land and Willemsen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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General composition of human milk oligosaccharides and synthetic analogs. (A) All HMOS consist of only 5 different monosaccharides. The chemical structures of these monosaccharides are presented in a D- configuration. (B) The composition of HMOS follows a distinct structure. Elongation of the core structure and decoration with fucose and/or sialic acid residues leads to the large number of different structures discovered to date. (C) As examples, six simple oligosaccharide structures are displayed.