Table 1.

Demographics and clinical characteristics of OCSCC and OPSCCs.

Cancer site	Oral cavity	Oropharynx (p16-negative)	Oropharynx (p16-positive)
Demographics	Tobacco (smoking, chewing, betel nut), alcohol Older More African-Americans Lower SES Lower education	Tobacco (smoking), alcohol Older More African-Americans Lower SES Lower education	Nonsmoker Male Younger Caucasian Increased sexual partners Higher SES Higher education
Common Locations	Oral tongue	Tonsil BOT Pharyngeal wall Soft palate	Tonsil BOT
Common Presentations	Soreness with red or white spots	Sore throat Dysphagia Otalgia Neck mass	Painless neck mass

HPV – human papillomavirus; SES – socioeconomic status; BOT – base of tongue.