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. 2020 May 7;11:804. doi: 10.3389/fmicb.2020.00804

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Copyright © 2020 Chen, Johnson, Yu, Nelson and Walker.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Deficiency in siderophore synthesis was susceptible to H2O2 damage and led to the attenuated biofilm formation. (A) The survival rate of WT cells in low iron media (LB added with 2′2-dipyridyl), LB media, high iron media, and LB media supplemented with hemoglobin. (B) The survival rate of mutants in low iron media (LB added with 2′2-dipyridyl), LB media, high iron media, and LB media supplemented with hemoglobin. (C) Biofilm formation of the WT and mutant cells grown in the low iron and high iron media. Values are means ± standard deviation. Asterisks indicate there was a significant difference (P < 0.05).