Table 4.
Laboratory changes of discharged common COVID-19 patients (N = 37)
| Parameters | Normal Range | Admission median (IQR) | Discharge median (IQR) | p |
|---|---|---|---|---|
| K+, mmol/L | 3.5–5.5 | 3.81 (3.66–4.10) | 4.25 (3.90–4.74) | 0.000** |
| Na+, mmol/L | 133–149 | 135.50 (134.35–136.75) | 137.20 (136.15–138.25) | 0.000** |
| Chlorine, mmol/L | 95–110 | 101.90 (98.90–103.05) | 101.90 (100.15–103.55) | 0.459a |
| Ca2+, mmol/L | 1.05–1.35 | 1.19 (1.17–1.21) | 1.22 (1.20–1.25) | 0.001a ** |
| ALT, U/L | 0–42 | 22.34 (14.82–29.07) | 23.07 (16.81–32.79) | 0.124a |
| AST, U/L | 0–37 | 23.38 (18.88–32.07) | 22.00 (17.75–29.50) | 0.064 |
| Total bilirubin, μmol/L | 3.4–20.5 | 12.43 (9.80–16.61) | 12.36 (8.99–17.06) | 0.504 |
| Direct bilirubin, μmol/L | 0–6.8 | 3.99 (2.95–6.35) | 3.54 (2.58–5.93) | 0.994 |
| Indirect bilirubin μmol/L | 5.1–13.7 | 8.48 (6.68–11.19) | 9.17 (6.63–12.40) | 0.226 |
| Total protein, g/L | 60–83 | 61.89 (59.37–63.81) | 64.85 (61.27–66.23) | 0.007** |
| Albumin, g/L | 35–55 | 36.22 (32.91–39.72) | 34.79 (32.82–39.85) | 0.777 |
| Globulin, g/L | 20.2–29.5 | 25.90 (23.30–28.50) | 27.60 (25.70–31.20) | 0.000** |
| Albumin/Globulin (A/G) | 1.50–2.50 | 1.42 (1.21–1.68) | 1.28 (1.08–1.51) | 0.003** |
| Total bile acid, μmol/L | 0.0–15 | 2.99 (1.79–5.63) | 4.13 (2.58–6.66) | 0.362a |
| BUN,mmol/L | 2.86–8.2 | 3.71 (2.97–4.38) | 4.42 (3.45–5.29) | 0.001** |
| Creatinine, μmol/L | 19.8–87.1 | 44.19 (40.18–51.72) | 55.70 (47.16–62.35) | 0.000** |
| UA, μmol/L | 149–430 | 226.70 (195.70–254.30) | 251.60 (193.10–304.50) | 0.044* |
| Glucose, mmol/L | 3.9–6.1 | 5.82 (4.98–6.93) | 5.34 (4.85–6.23) | 0.003** |
| CK, U/L | 10–190 | 63.70 (37.40–97.30) | 35.70 (28.15–54.60) | 0.000a ** |
| CK-MB, U/L | 0–24 | 10.20 (6.80–12.20) | 7.20 (4.50–11.25) | 0.062 |
| LDH, U/L | 135–225 | 172.70 (133.60–206.80) | 165.10 (140.90–193.10) | 0.167 |
| Hs-CRP mg/L | 0.0–8.0 | 17.05 (6.65–29.36) | 9.88 (4.87–22.31) | 0.007** |
| WBC count, × 109/L | 4–10 | 4.58 (3.27–5.45) | 6.28 (5.32–7.92) | 0.000a ** |
| RBC count, × 1012/L | 3.50–5.5 | 4.39 (4.07–4.65) | 4.37 (4.20–4.70) | 2.242 |
| Hemoglobin, g/L | 110–160 | 127.00 (118.00–139.50) | 129.00 (121.00–140.00) | 2.220 |
| Platelet count, × 109/L | 100–300 | 173.00 (134.50–229.00) | 277.00 (203.50–324.50) | 0.000** |
| Hematocrit, % | 37.0–54.0 | 39.10 (36.70–42.35) | 40.20 (37.20–42.50) | 0.048* |
| MCV, fl | 80–100 | 90.90 (88.25–92.95) | 90.80 (87.95–92.90) | 0.293 |
| MCH, pg | 27.0–34.0 | 29.20 (28.50–29.85) | 29.30 (28.60–29.80) | 0.941 |
| MCHC, g/L | 320–360 | 323.00 (319.00–328.50) | 323.00 (318.00–326.00) | 0.648a |
| Lymphocyte ratio, % | 20–40 | 27.00 (19.65–30.60) | 26.10 (17.55–30.15) | 0.484a |
| Monocyte ratio, % | 3.0–12.0 | 7.60 (6.30–9.50) | 7.50 (6.20–9.30) | 0.521a |
| Neutrophil ratio, % | 50.0–70.0 | 64.90 (60.30–72.45) | 66.40 (59.65–72.70) | 0.566 |
| Eosinophil ratio, % | 0.5–5.0 | 0.30 (0.10–1.00) | 1.30 (0.60–2.05) | 0.014* |
| Basophil ratio, % | 0.0–1.0 | 0.30 (0.20–0.30) | 0.30 (0.20–0.40) | 0.071a |
| Lymphocyte count, × 109/L | 0.8–4.0 | 1.12 (0.91–1.42) | 1.60 (1.21–1.87) | 0.000** |
| Monocyte count, × 109/L | 0.12–1.2 | 0.35 (0.27–0.42) | 0.46 (0.36–0.61) | 0.003** |
| Neutrophil count, × 109/L | 2.00–7.00 | 2.93 (1.98–3.72) | 4.26 (3.21–5.67) | 0.002** |
| Eosinophil count, × 109/L | 0.02–0.5 | 0.01 (0.00–0.05) | 0.09 (0.04–0.12) | 0.000** |
| Basophil count, × 109/L | 0.00–0.10 | 0.01 (0.01–0.02) | 0.02 (0.01–0.03) | 0.000a ** |
| RDW-CV | 11.0–16.0 | 12.00 (11.80–12.50) | 12.00 (11.70–12.45) | 0.205a |
| RDW-SD | 35.0–56.0 | 38.50 (37.10–39.75) | 37.80 (36.90–39.00) | 0.081* |
| PDW, % | 9.0–17.0 | 16.40 (16.05–16.70) | 16.40 (16.15–16.60) | 0.778 |
| MPV, fl | 6.5–12.0 | 9.50 (8.95–10.85) | 9.60 (8.80–10.10) | 0.230 |
| Plateletocrit, % | 0.108–0.282 | 0.16 (0.13–0.22) | 0.26 (0.21–0.29) | 0.000** |
Data are given as median (IQR). P values indicate differences between discharged and admission patients by paired-sample t test
ap values are determined by Mann–Whitney test
*p < 0.05, **p < 0.01 was considered statistically significant