Table 5.

Comparison of differential values (DV) (discharge -admission) in COVID-19 patients with different treatment (N = 37)

Drugs	Parameters	Did not receive the treatment	Received the treatment	p
IFN-α2b (received N = 18)	K+, mmol/L	0.24 (− 0.17 to 0.59)	0.675 (0.41–1.03)	0.001**
	Ca2+, mmol/L	0.01(− 0.20 to 0.05)	0.04 (0.01–0.63)	0.013*
	Total bilirubin, μmol/L	3.00(− 3.31 to 10.09)	− 1.79 (− 5.75 to 3.16)	0.025*
Corticosteroids (received N = 11)	Total bile acid, μmol/L	− 0.32 (− 2.50 to 2.12)	3.93 (− 0.04 to 8.68)	0.044*a
	BUN, mmol/L	0.55 (− 0.29 to 1.24)	1.92 (0.40–2.91)	0.002*
	CK, U/L	− 8.90 (− 43.05 to 2.30)	− 47.60 (− 60.30 to 13.70)	0.031*a
	Basophil ratio, %	0.30 (0.20–0.40)	0.20 (0.10–0.20)	0.005**a
	Basophil count, × 109/L	0.01 (0.01–0.02)	0.01 (0.00–0.01)	0.024*a
	MPV, fl	9.65 (9.18–11.00)	9.00 (8.40–.90)	0.048*a
Nova (received N = 13)	BUN, mmol/L	1.225 (0.48–2.08)	− 0.25(− 0.88 to 0.63)	0.000**
	CK, U/L	− 31.5 (− 66.9 to 8.9)	− 3.9 (− 31.35 to 13.85)	0.018**a
Antibiotic (received N = 22)	Total bilirubin, μmol/L	− 3.31 (− 5.35 to 2.06)	2.76 (− 1.85 to 8.04)	0.042*a
	Indirect bilirubin, μmol/L	− 2.08 (− 3.79 to 1.07)	3.29 (− 1.15 to 6.24	0.008**a
	Total bile acid, μmol/L	− 1.24 (− 3.21 to 0.09)	1.185 (− 0.37 to 4.92)	0.027*a
	Creatinine, μmol/L	13.8 (5.89–34.14)	5.66 (− 1.76 to 11.71)	0.028*a
	Platelet count, × 109/L	236 (139.00–293.00)	147 (128.30–193.80)	0.016*
	Plateletocrit, %	0.22 (0.14–0.25)	0.15 (0.13–0.18)	0.010*

Data are given as median (IQR). P values indicate differences between unused and used patients

^ap values are determined by Mann–Whitney test

*p < 0.05, **p < 0.01 was considered statistically significant